I've never used any creatine with no2 type stuff but I have used NO2 as a standalone. It's ok but IMO a waste of money. I didn't really see much pump using it. I don't knwo how well it gels with the creatine but I just cycle creatine. In my honest opinon ffrom a fellow meathead... WASTE of money like that new GAICK shit from musltech.. waste....